Neurotransmitters: The critical modulators regulating gut-brain axis

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RAHUL MITTAL, LUCA H. DEBS, AMIT P. PATEL, DESIREE NGUYEN, KUNAL PATEL, GREGORY O’CONNOR, M’HAMED GRATI, JEENU MITTAL, DENISE YAN, ADRIEN A. ESHRAGHI, SAPNA K. DEO, SYLVIA DAUNERT AND XUE ZHONG LIU |

It has recently become evident that the gut microbiota has the ability to influence physiological aspects of the body, including a direct communication to the brain from the gut (O’Mahony et al., 2015). In that regard, the gut microbiota has demonstrated unique functions associated with behavior, mood, and cognition that are currently being explored. The gut microbiota can interact with the chemical messengers involved in the transmission of information including monoamines such as 5-hydroxytryptamine (5-HT), also known as serotonin.